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Scripts and data related to the manuscript titled "Metabolic task analysis reveals distinct metabotypes in end-stage dilated cardiomyopathy"

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MetabolicTasksDCM

Scripts and data related to the manuscript titled "Metabolic task analysis reveals distinct metabotypes in end-stage dilated cardiomyopathy"

The manuscript is available as a preprint on Biorxiv (https://doi.org/10.1101/2025.03.28.645901)

This repository is currently under revision as preparation for publication, and therefore subject to change.

Run order

Subscripts

R scripts and function in the R/Subscripts folder will be sourced as required. Matlab scripts in the Matlab/Subscripts folder must be added to the Matlab Path before running any of the other Matlab scripts.

Main scripts

The first scripts which should be run are:

  • 1st the R scripts numbered "0", to preprocess the expression data.
  • 2nd the Matlab script "N0_task_analysis_essential_rxns.m", to generate essential reactions required for CellFie

Then, the other Metlab scripts can be run. Finally, the remaining R scripts can be run in their numbered order.

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Scripts and data related to the manuscript titled "Metabolic task analysis reveals distinct metabotypes in end-stage dilated cardiomyopathy"

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