Low Sample Matching in MICOM Model

[dorarinyo88]

I am trying to build a MICOM model using abundance data generated from Paprica, with preprocessing applied to match MICOM’s expected format. However, I am encountering the following warning when running MICOM:
Less than 50% of the abundance could be matched to the model database. Model community.py:229 sample_1105 may not be representative of the sample.

Additionally, when checking the manifest file, I noticed that none of my taxa were found in the MICOM model database, leading to a found_abundance_fraction of 0.0 for all samples.

Dataset Information

• The taxonomy and abundance values were generated using Paprica.
• Preprocessing was done to format it for MICOM.
• Here is an example of my dataset before processing:

The manifest file shows that no taxa were matched in MICOM:

Would appreciate any guidance on resolving this issue. Thanks!

[cdiener]

Hi,

So your taxa don't look right. The genus seems to be wrong for all of them. funiformis is Megamonas and Firmicutes is a phylum not a genus. copri would the Prevotella genus. MICOM always matches on as many ranks as possible, so in that case none of the genera match.