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Reaction MAR04356, which represents D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase (ALDOB, EC 4.1.2.13) is shown as unidirectional: DHAP + glyceraldehyde -> fructose 1-P
When in reality it is bidirectional: DHAP + glyceraldehyde <-> fructose 1-P
The absence of the reverse reaction prevents this from serving as a route of fructose oxidation
Source from KEGG (which is linked in the model itself by the way) Source from Hannou et al., 2018
The text was updated successfully, but these errors were encountered:
This work also proves that F1P can be a substrate for ALDOB (Table 1), so I agree to change MAR04356 to be reversible.
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Reaction MAR04356, which represents D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase (ALDOB, EC 4.1.2.13) is shown as unidirectional:
DHAP + glyceraldehyde -> fructose 1-P
When in reality it is bidirectional:
DHAP + glyceraldehyde <-> fructose 1-P
The absence of the reverse reaction prevents this from serving as a route of fructose oxidation
Source from KEGG (which is linked in the model itself by the way)
Source from Hannou et al., 2018
The text was updated successfully, but these errors were encountered: