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Scipion is an image processing framework for obtaining 3D models of macromolecular complexes using Electron Microscopy (3DEM). It integrates several software packages and presents a unified interface for both biologists and developers. Scipion allows you to execute workflows combining different software tools, while taking care of formats and conversions. Additionally, all steps are tracked and can be reproduced later on.

Getting Started

• See this ~5 minutes Introductory Video that shows an overview of Scipion.

• Follow this step-by-step guide about How to Install Scipion.

• Complete the Mix-and-Match Tutorial illustrating how to use several packages.

• Take a look at the list of current integrated Packages and Protocols.

More Documentation

• Users Page: introductory resources that assume a basic knowledge of electron microscopy. Current tutorials include: (1) Introduction to SPA in Scipion using BPV data, (2) Initial volume estimation with several methods: RCT, Ransac, Eman

• Developers Page: Has information about software tools provided by the Scipion framework. This section can be useful even for a non-programmer experimentalist.